NATIONAL CHIAO TUNG UNIVERSITY

INSTITUTE OF STATISTICS

 

INTRODUCTION TO EPIDEMIOLOGY

FALL 2007

 

 

 


Instructor:

Guan-Hua Huang, Ph.D.

 

Office: 423 Joint Education Hall

 

Phone: 03-513-1334

 

Email: ghuang@stat.nctu.edu.tw

Class meetings:

Wednesday 9:00 am-12:00 pm at 427 Joint Education Hall

Office hours:

By appointment

Class website:

http://www.stat.nctu.edu.tw/subhtml/source/teachers/ghuang/course/introepif07/

 

Credit:

Three (3) credits

 

COURSE SUMMARY

 

The main purpose of this course is to expose students to a variety of key epidemiologic concepts and ways to approach these concepts when carrying out epidemiologic studies.

 

At the conclusion of this course, you should

 

 

HANDOUTS AND TEXTBOOKS

 

Handouts corresponding to each lecture will be available on the class website before each class. The required textbook for this course is

 

Leon Gordis (2000), Epidemiology, 2nd edition, W. B. Saunders Co.

 

Reading assignments will be made primary in this book. In addition, one book is suggested for recommend reading

 

David E. Lilienfeld and Paul D. Stolley (1994), Foundations of Epidemiology, 3rd edition, Oxford University Press.

 

Students are also encouraged to get an English-Chinese medical dictionary to facilitate the course.

 

INTENDED AUDIENCE

 

The course will be of interest to students who want to learn about the foundation science for epidemiology. There are no prerequisites for this course.

 

METHOD OF STUDENT EVALUATION

 

The course grade will be based on three homework assignments (30%), one midterm exam (30%), and one final exam (40%). The midterm exam will be held on November 14 (9:00 am-12:00 pm) (Notice: this is not in the “regular” midterm week; it’s one week later), and the final exam will on January 9 (9:00 am-12:00 pm).

 

COURSE OUTLINE

 

Readings refer to Gordis (2000), Epidemiology, 2nd edition, W. B. Saunders Co. (Gordis), and Lilienfeld and Stolley (1994), Foundations of Epidemiology, 3rd edition, Oxford University Press (Lilienfeld and Stolley).

 

Sep 12

Lecture

Orientation: format, grading, readings

Epidemiologic approach to health and disease

 

Reading

Gordis

-

Chapter 1

Lilienfeld and Stolley

-

Chapter 1

 

 

 

Sep 19

Lecture

Epidemiologic concepts: transmission of disease and investigation of an epidemic

 

Reading

Gordis

-

Chapter 2

Lilienfeld and Stolley

-

Chapter 1, pp. 13-19

Chapter 3

 

 

 

Sep 26

Lecture

Measuring the occurrence of disease: morbidity and mortality

 

Reading

Gordis

-

Chapter 3

Lilienfeld and Stolley

-

Chapter 4

Chapter 6, pp. 101-105, 109-117

 

 

 

Oct 3

Lecture

Assessing diagnostic and screening tests: validity and reliability

 

Reading

Gordis

-

Chapter 4

Lilienfeld and Stolley

-

Chapter 6, pp. 117-125

 

 

 

Oct 10

Lecture

National holiday: no class

 

 

 

Oct 17

Lecture

The natural history of disease: ways to express prognosis

 

Reading

Gordis

-

Chapter 5

Lilienfeld and Stolley

-

Chapter 10, pp. 218-220

 

 

 

Oct 24

Lecture

Study design I: clinical trials

 

Reading

Gordis

-

Chapters 6, 7

Lilienfeld and Stolley

-

Chapters 8, 9

 

 

 

Oct 31

Lecture

Study design II: cohort studies

 

Reading

Gordis

-

Chapter 8

Lilienfeld and Stolley

-

Chapter 10, pp. 198-200, 205-218

 

Assignment

Homework 1 due

 

 

 

Nov 7

Lecture

Study design III: case-control and cross-sectional studies

 

Reading

Gordis

-

Chapter 9

Lilienfeld and Stolley

-

Chapter 6, pp. 106-109

Chapter 11, pp. 226-231, 245-248

 

 

 

Nov 14

Lecture

Midterm examination

 

 

 

 

 

 

Nov 21

Lecture

Measuring the risk of disease: association

 

Reading

Gordis

-

Chapters 10, 11, 12

Lilienfeld and Stolley

-

Chapter 10, pp. 200-205

Chapter 11, pp. 239-245

 

 

 

Nov 28

Lecture

Deriving inferences from epidemiologic studies: association versus causation

 

Reading

Gordis

-

Chapter 13

Lilienfeld and Stolley

-

Chapter 12

 

 

 

Dec 5

Lecture

Interpretation of epidemiologic data: bias, confounding and interaction

 

Reading

Gordis

-

Chapter 14

Lilienfeld and Stolley

-

Chapter 10, pp. 220-221

Chapter 11, pp. 231-238

Chapter 12, pp. 256-261

 

Assignment

Homework 2 due

 

 

 

Dec 12

Lecture

Guest lecture: Genetic epidemiology

 

 

Reading

Gordis

-

Chapter 15

Lilienfeld and Stolley

-

Chapter 5, pp. 84-89

 

 

 

Dec 19

Lecture

Guest lecture: Psychiatry epidemiology

 

Dec 26

Lecture

Guest lecture: Infectious disease epidemiology

 

 

 

 

Jan 2

Lecture

Legal, ethical and policy aspects of epidemiologic investigations

 

Reading

Gordis

-

Chapter 18, 19

Lilienfeld and Stolley

-

?

 

Assignment

Homework 3 due

 

 

 

Jan 9

Lecture

Final examination