NATIONAL 
CHIAO TUNG UNIVERSITY
INSTITUTE 
OF STATISTICS
 
INTRODUCTION 
TO EPIDEMIOLOGY
FALL 
2003
 
 
  
| Instructor: | Guan-Hua 
      Huang, Ph.D. | 
|   | Office: 
      423 Assembly Building 1 | 
|   | Phone: 
      03-513-1334 | 
|   | Email: 
      ghuang@stat.nctu.edu.tw | 
| Class 
      meetings: | Wednesday 
      1:30-4:30 pm at 427 Assembly Building 1 | 
| Office 
      hours: | Wednesday 
      10:00am-12:00pm at 423 Assembly Building 1 | 
| Class 
      website: | http://www.stat.nctu.edu.tw/faculty/ghuang/course/introepif03/ | 
| Credit: | Three 
      (3) credits | 
 
The main 
purpose of this course is to expose students to a variety of key epidemiologic 
concepts and ways to approach these concepts when carrying out epidemiologic 
studies. 
 
At the 
conclusion of this course, you should 
 
 
 
Handouts 
corresponding to each lecture will be available on the class website before each 
class. The required textbook for this course is
 
Leon 
Gordis (2000), Epidemiology, 
2nd edition, W. B. Saunders Co. 
 
Reading 
assignments will be made primary in this book. In addition, one book is 
suggested for recommend reading
 
David E. 
Lilienfeld 
and Paul D. 
Stolley (1994), Foundations 
of Epidemiology, 3rd edition, Oxford 
University Press.
 
Students 
are also encouraged to get an English-Chinese medical dictionary to facilitate 
the course.
 
 
The 
course will be of interest to students who want to learn about the foundation 
science for epidemiology. There are no prerequisites for this 
course.
 
 
The 
course grade will be based on three homework assignments (30%), one midterm exam 
(30%), and one final exam (40%). 
 
COURSE 
OUTLINE 
 
Readings 
refer to Gordis (2000), Epidemiology, 2nd edition, W. B. Saunders Co. (Gordis), 
and Lilienfeld 
and Stolley 
(1994), Foundations of Epidemiology, 3rd edition, Oxford 
University Press (Lilienfeld 
and Stolley).
 
| Sep 
      10 | Lecture | Orientation: 
      format, grading, readings Epidemiologic 
      approach to health and disease | ||||||
|   | Reading | 
 | ||||||
|   |   |   | ||||||
| Sep 
      17 | Lecture | Epidemiologic concepts: 
      transmission of disease and investigation of an epidemic | ||||||
|   | Reading | 
 | ||||||
|   |   |   | ||||||
| Sep 
      24 | Lecture | Measuring the occurrence of 
      disease: morbidity and mortality | ||||||
|   | Reading | 
 | ||||||
|   |   |   | ||||||
| Oct 
      1 | Lecture | Assessing diagnostic and 
      screening tests: validity and reliability | ||||||
|   | Reading | 
 | ||||||
|   |   |   | ||||||
| Oct 
      8 | Lecture | The 
      natural history of disease: ways to express prognosis | ||||||
|   | Reading | 
 | ||||||
|   |   |   | ||||||
| Oct 
      15 | Lecture | Study 
      design I: clinical trials | ||||||
|   | Reading | 
 | ||||||
|   | Assignment | Homework 
      1 due | ||||||
|   |   |   | ||||||
| Oct 
      22 | Lecture | Study 
      design II: cohort studies | ||||||
|   | Reading | 
 | ||||||
|   |   |   | ||||||
| Oct 
      29 | Lecture | Study 
      design III: case-control and cross-sectional studies | ||||||
|   | Reading | 
 | ||||||
|   |   |   | ||||||
| Nov 
      5 | Lecture | Midterm 
      examination | ||||||
|   |   |   | ||||||
| Nov 
      12 | Lecture | Measuring the risk of disease: 
      association | ||||||
|   | Reading | 
 | ||||||
|   |   |   | ||||||
| Nov 
      19 | Lecture | Deriving inferences from 
      epidemiologic studies: association versus causation | ||||||
|   | Reading | 
 | ||||||
|   | Assignment | Homework 
      2 due | ||||||
|   |   |   | ||||||
| Nov 
      26 | Lecture | Interpretation of 
      epidemiologic data: bias, confounding and interaction | ||||||
|   | Reading | 
 | ||||||
|   |   |   | ||||||
| Dec 
      3 | Lecture | University athletic activity: 
      no class | ||||||
|   |   |   | ||||||
| Dec 
      10 | Lecture | Genetic epidemiology 
       Dr. Yen-Feng Chiu, Division of 
      Biostatistics and Bioinforrmatics, National Health Research 
      Institutes | ||||||
|   | Reading | 
 | ||||||
|   |   |   | ||||||
| Dec 
      17 | Lecture | Psychiatry 
      epidemiology Dr. Angela P. Fan, 
      Department 
      of Psychiatry, National Yang-Ming 
  University | ||||||
|   | Assignment | Homework 
      3 due | ||||||
|   |   |   | ||||||
| Dec 
      24 | Lecture | Infectious disease 
      epidemiology Dr. Yu-Hsiang 
      Hsieh, 
      Department 
      of Public Health, National Cheng Kung University | ||||||
|   |   |   | ||||||
| Dec 
      31 | Lecture | Legal, ethical and policy 
      aspects of epidemiologic investigations | ||||||
|   | Reading | 
 | ||||||
|   |   |   | ||||||
| Jan 
      7 | Lecture | Final 
      examination | ||||||
|   |   |   |