GENERALIZED LINEAR MODELS
SPRING
2007

| Instructor: | Guan-Hua Huang, Ph.D. | 
|  | Office: 423 Joint Education Hall | 
|  | Phone: 03-513-1334 | 
|  | Email: ghuang@stat.nctu.edu.tw | 
| Class meetings: | Wednesday 9:00 am -12:00 pm at 407 Joint Education Hall | 
| Office hours: | By appointment | 
| Class website: | http://www.stat.nctu.edu.tw/subhtml/source/teachers/ghuang/course/glm07/ | 
| Credit: | Three (3) credits | 
The objects of his course are
          
To present regression
methodologies for categorical and count responses unified under the framework
of generalized linear models.
          
To familiarize the usage of
statistical software implementing these regression methodologies.
          
To provide references for your
future research.
Topics include review of likelihood inference and
large sample test statistics; generalized linear models framework; analysis of
binary, polytomous and count data; and estimating functions.
Handouts corresponding to each lecture will be
available on the class website before each class. There is one required textbook for this course and reading assignments will be made
primary in this book:
McCullagh P. and Nelder
J.A. (1989). Generalized
Linear Models, 2nd edition. Chapman and Hall.
Students are expected to have
background on undergraduate probability, mathematical statistics, and linear
regression.
The course grade will be based on five homework assignments (50%), one midterm exam (20%), and one final exam (30%). 
COURSE OUTLINE 
| Module | Topic  |  | 
| 1 | Review        
  Likelihood function and some
  basic properties        
  Exponential family        
  Three large sample test        
  Conditional likelihood
  inference |  | 
| 2 | Generalized linear
  models (GLM)        
  The
  origins of GLM        
  Systematic
  and random components of GLM        
  Some
  statistical properties of GLM        
  Maximum
  likelihood estimation versus weighted least squares        
  Deviance
  – a measure of goodness-of-fit        
  Iterative
  reweighted least squares algorithm | Chapter 2 | 
| 3 | Analysis of binary data        
  Binomial
  distribution        
  Link
  functions        
  Case-control
  applications        
  Over-dispersion | Chapter 4 | 
| 4 | Analysis of polytomous
  data        
  Multinomial
  distribution        
  Model
  for nominal scales        
  Model
  for ordinal scales        
  Nested
  or hierarchical response scales | Chapter 5 | 
| 5 | Analysis of count data        
  Poisson
  distribution        
  Log-linear
  model for contingency tables        
  Connection
  with multinomial model        
  Poisson
  regression – application to cohort studies | Chapter 6 | 
| 6 | Quasi-likelihood
  function and estimating functions        
  Construction
  of quasi-likelihood function        
  Optimal
  estimating functions        
  Some
  applications of estimating functions | Chapter 9 |