GENERALIZED
LINEAR (AND ADDITIVE) MODELS
FALL 2009

| Instructor: | Guan-Hua Huang, Ph.D. | 
|  | Office: 423 Joint Education Hall | 
|  | Phone: 03-513-1334 | 
|  | Email: ghuang@stat.nctu.edu.tw | 
| Class meetings: | Thursday 9:00-12:00 at 407 Joint Education Hall | 
| Office hours: | By
  appointment | 
| Class website: | |
| Credit: | Three (3) credits | 
The objects of his course are
   To present regression methodologies for categorical and count responses
unified under the framework of generalized linear models and generalized
additive models.
   To familiarize the usage of statistical software implementing these regression
methodologies.
   To provide references for your future research.
Topics include review of likelihood inference and
large sample test statistics, generalized linear models framework, analysis of
binary, polytomous and count data, smoothing, additive models and generalized
additive models.
Handouts corresponding to each lecture
will be available on the class website before each class. Reading assignments are from the following two books:
  
McCullagh P. and Nelder J.A. (1989). Generalized
Linear Models, 2nd edition. Chapman and Hall.
  
Hastie T.J. and Tibshirani R.J. (1990). Generalized
Additive Models. Chapman and Hall.
Students
are expected to have background on undergraduate probability, mathematical
statistics, and linear regression.
The course grade will be based on four homework assignments (50%), one midterm
exam (20%),
and one final exam (30%).
COURSE OUTLINE 
McCullagh
P. and Nelder J.A. (1989): Generalized Linear Models, 2nd edition.
(McCullagh & Nelder)
Hastie T.J.
and Tibshirani R.J. (1990). Generalized Additive Models. (Hastie &
Tibshirani)
| Module | Topic  |  | 
| 1 | Review  
  Likelihood
  function and some basic properties  
  Exponential
  family  
  Three large
  sample test  
  Conditional
  likelihood inference |  | 
| 2 | Generalized
  linear models (GLM)  
  The origins of GLM  
  Systematic and random components of GLM  
  Some statistical properties of GLM  
  Maximum likelihood estimation versus weighted least squares  
  Deviance - a measure of goodness-of-fit  
  Iterative reweighted least squares algorithm | McCullagh
  & Nelder  Chapter 2 | 
| 3 | Analysis
  of binary data  
  Binomial distribution  
  Link functions  
  Case-control applications | McCullagh
  & Nelder  Chapter 4 | 
| 4 | Analysis
  of polytomous data  
  Multinomial distribution  
  Model for nominal scales  
  Model for ordinal scales  
  Nested or hierarchical response scales | McCullagh
  & Nelder  Chapter 5 | 
| 5 | Analysis
  of count data  
  Poisson distribution  
  Log-linear model for contingency tables  
  Connection with multinomial model  
  Poisson regression – application to cohort studies | McCullagh
  & Nelder  Chapter 6 | 
| 6 | Smoothing  
  Bin smoothers  
  Kernel smoothers  
  Splines | Hastie
  & Tibshirani  Chapter 2 | 
| 7 | Additive
  models  
  Fitting additive models  
  Estimating equations for additive models  
  Solutions to the estimating equations | Hastie
  & Tibshirani  Chapters 4, 5 | 
| 8 | Generalized
  additive models (GAM)  
  Local scoring for GAM  
  Semi-parametric GAM  
  Inferences  
  Smoothing parameter selection | Hastie
  & Tibshirani  Chapter 6 |